This web page was produced as an assignment for Genetics 677, an undergraduate course at UW-Madison
Microarrays
http://bioinfoworld.files.wordpress.com/2008/10/microarray.jpg
While all bodily cells contain full copies of an individual's genome, expression of that genome varies drastically from cell type to cell type, generally, temporally, and conditionally. Transcriptional regulators determine how much mRNA is produced, which will eventually translate into protein (for the most part). Microarrays allow scientists to relatively assay levels of mRNA in cells under a normal controlled state or time in the life cycle, and compare that to some treated or time-variant group. Below is a link to one such study on chicken cdh23 mRNA.
Reference: Microarray Factsheet, NCBI:
http://www.ncbi.nlm.nih.gov/About/primer/microarrays.html
http://www.ncbi.nlm.nih.gov/About/primer/microarrays.html
Ben Hofeld, [email protected], last updated: 5.15.2010, Link to course page:www.gen677.weebly.com
